Monster labs MK677
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Mk 677 is an orally administrated GH secretagogue originally developed by Monster labs . A secretagogue is a term for a substance that chemically signals for the pituitary gland to secrete GH. In other words, MK 677 could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn’t require any injections nor does it have any side effects like GHRP-6. MK 677 was developed in an aim to combat such conditions as muscle wasting, obesity, and osteoporosis. It was also targeted towards the treatment of elderly hip fracture patients, so there are a myriad of studies done on safety.
How it Works: Growth hormone pulse intensity can be increased through 4 possible mechanisms*:
Increasing GHRH (growth hormone releasing hormone) release.
Amplifying GHRH signaling in somatotrophs of the anterior pituitary gland.
Reducing somatostatin release (somatostatin turns off GH release).
Inhibiting of somatostatin receptor signaling.
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